Only if you are protecting proprietary content you do not want reproduced. For most businesses, blocking AI crawlers removes you from AI answers entirely — which means removal from the shortlist buyers form before they contact anyone.
Blocking is often accidental — security plugins and CDN rules block unknown user agents by default.
Check your robots.txt and firewall logs for GPTBot, ClaudeBot, PerplexityBot, and Google-Extended.
An explicit allowlist is more durable than relying on a blanket allow rule.